Titanium dioxide-cellulose hybrid nanocomposite and its glucose biosensor application

Mohammad Maniruzzaman, Sang Dong Jang, Jaehwan Kim

Research output: Contribution to journalArticlepeer-review

45 Scopus citations

Abstract

This paper investigates the fabrication of titanium dioxide (TiO 2)-cellulose hybrid nanocomposite and its possibility for a conductometric glucose biosensor. TiO2 nanoparticles were blended with cellulose solution prepared by dissolving cotton pulp with lithium chloride/N,N-dimethylacetamide solvent to fabricate TiO2-cellulose hybrid nanocomposite. The enzyme, glucose oxidase (GOx) was immobilized into this hybrid nanocomposite by physical adsorption method. The successful immobilization of glucose oxidase into TiO2-cellulose hybrid nanocomposite via covalent bonding between TiO2 and GOx was confirmed by X-ray photoelectron analysis. The linear response of the glucose biosensor is obtained in the range of 1-10 mM. This study demonstrates that TiO 2-cellulose hybrid nanocomposite can be a potential candidate for an inexpensive, flexible and disposable glucose biosensor.

Original languageEnglish
Pages (from-to)844-848
Number of pages5
JournalMaterials Science and Engineering B: Solid-State Materials for Advanced Technology
Volume177
Issue number11
DOIs
StatePublished - 25 Jun 2012

Keywords

  • Cellulose
  • Glucose biosensor
  • Hybrid nanocomposite
  • Titanium dioxide

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