Abstract
This paper investigates the fabrication of titanium dioxide (TiO 2)-cellulose hybrid nanocomposite and its possibility for a conductometric glucose biosensor. TiO2 nanoparticles were blended with cellulose solution prepared by dissolving cotton pulp with lithium chloride/N,N-dimethylacetamide solvent to fabricate TiO2-cellulose hybrid nanocomposite. The enzyme, glucose oxidase (GOx) was immobilized into this hybrid nanocomposite by physical adsorption method. The successful immobilization of glucose oxidase into TiO2-cellulose hybrid nanocomposite via covalent bonding between TiO2 and GOx was confirmed by X-ray photoelectron analysis. The linear response of the glucose biosensor is obtained in the range of 1-10 mM. This study demonstrates that TiO 2-cellulose hybrid nanocomposite can be a potential candidate for an inexpensive, flexible and disposable glucose biosensor.
Original language | English |
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Pages (from-to) | 844-848 |
Number of pages | 5 |
Journal | Materials Science and Engineering B: Solid-State Materials for Advanced Technology |
Volume | 177 |
Issue number | 11 |
DOIs | |
State | Published - 25 Jun 2012 |
Keywords
- Cellulose
- Glucose biosensor
- Hybrid nanocomposite
- Titanium dioxide