Systemic optimization of microalgae for bioactive compound production

Jeong Dong Kim, Choul Gyun Lee

Research output: Contribution to journalReview articlepeer-review

22 Scopus citations

Abstract

The complexity of the biological system/biological systems has been fascinating and challenging for a long time. With the advent of mathematical tools with various omics technology, systems biology was born and is already ubiquitous in every area of biology and biotechnology. Microalgal biotechnology is no exception in this new trend. As tens of microalgal genomes become publicly available on the Internet, vast amounts of data from genomics, transcriptomics, and proteomics are reported everyday. Though there has not yet been enough data gathered on microalgal metabolomics, the in silico models for relatively simple cyanobacteria or for organelles, such as chloroplasts, will appear presently. With the help of systems biology, a more in-depth understanding of microalgae will be possible. Consequently, most industrially-interested microalgae can be metabolically redesigned/reconfigured as cell factories. Microalgae will be served as the hosts in white biotechnology.

Original languageEnglish
Pages (from-to)418-424
Number of pages7
JournalBiotechnology and Bioprocess Engineering
Volume10
Issue number5
DOIs
StatePublished - 2005

Bibliographical note

Funding Information:
^ÅâåçïäÉÇÖÉãÉåí This work was supported by Systems Biology Program from Inha University, for which the authors are grateful.

Keywords

  • Cyanobacteria
  • In silico
  • Metabolic reconstruction
  • Microalgae
  • Optimization
  • Systems biology

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