Straightforward microfluidic system for behavioral responses analysis of C. elegans to physical cues

Sunhee Yoon, Tae Joon Jeon, Sun Min Kim

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Caenorhabditis elegans (C. elegans), a prominent model organism, has interesting behavioral responses to various physical cues. In this study, we demonstrated a straightforward microfluidic system for the analysis of electrotaxis and thermotaxis of C. elegans. We compared total 5 strains of C. elegans, wild type (N2), mutants (unc-54(s74), unc-54(s74), ttx-7(nj50), tax-4(p678)) using this device. We believe that our microfluidic system will provide a standard platform for behavioral study of C. elegans with simple handling.

Original languageEnglish
Title of host publicationMicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages913-914
Number of pages2
ISBN (Electronic)9781733419017
StatePublished - 2020
Event24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020 - Virtual, Online
Duration: 4 Oct 20209 Oct 2020

Publication series

NameMicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020
CityVirtual, Online
Period4/10/209/10/20

Bibliographical note

Publisher Copyright:
© 2020 CBMS-0001

Keywords

  • Caenorhabditis elegans (C. elegans)
  • Electrotaxis
  • Microfluidic platform
  • Physical cues
  • Thermotaxis

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