Sesquiterpenoids and other constituents from Senecio argunensis

Wei Dong Xie; Yu Fang Niu; Peng Xiang Lai; Kyung Ho Row

doi:10.1248/cpb.58.991

Sesquiterpenoids and other constituents from Senecio argunensis

Wei Dong Xie, Yu Fang Niu, Peng Xiang Lai, Kyung Ho Row

Shandong University

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

Three new sesquiterpenoids, isodauc-7(14)-en-6α,10β-diol (1), 10β-hydroxyisodauc-6-en-14-al (2), and (7S*)-opposit-4(15)-en-1 β,7-diol (4), along with ten known compounds have been isolated from the aerial parts of Senecio argunensis. Their structures were established by means of detailed spectroscopic analysis including IR, HR-MS, and 1D NMR and 2D NMR data. The sesquiterpenoids were assayed against Escherichia coli, Staphylococcus aureus and Bacillus subtilis. Compounds 4 exhibited weak antibacterial activity against Escherichia coli and Bacillus subtilis.

Original language	English
Pages (from-to)	991-994
Number of pages	4
Journal	Chemical and Pharmaceutical Bulletin
Volume	58
Issue number	7
DOIs	https://doi.org/10.1248/cpb.58.991
State	Published - Jul 2010

Keywords

Antibacterial
Isodaucane
Oppositane
Senecio argunensis
Sesquiterpenoid

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10.1248/cpb.58.991

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abstract = "Three new sesquiterpenoids, isodauc-7(14)-en-6α,10β-diol (1), 10β-hydroxyisodauc-6-en-14-al (2), and (7S*)-opposit-4(15)-en-1 β,7-diol (4), along with ten known compounds have been isolated from the aerial parts of Senecio argunensis. Their structures were established by means of detailed spectroscopic analysis including IR, HR-MS, and 1D NMR and 2D NMR data. The sesquiterpenoids were assayed against Escherichia coli, Staphylococcus aureus and Bacillus subtilis. Compounds 4 exhibited weak antibacterial activity against Escherichia coli and Bacillus subtilis.",

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author = "Xie, {Wei Dong} and Niu, {Yu Fang} and Lai, {Peng Xiang} and Row, {Kyung Ho}",

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AU - Xie, Wei Dong

AU - Niu, Yu Fang

AU - Lai, Peng Xiang

AU - Row, Kyung Ho

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AB - Three new sesquiterpenoids, isodauc-7(14)-en-6α,10β-diol (1), 10β-hydroxyisodauc-6-en-14-al (2), and (7S*)-opposit-4(15)-en-1 β,7-diol (4), along with ten known compounds have been isolated from the aerial parts of Senecio argunensis. Their structures were established by means of detailed spectroscopic analysis including IR, HR-MS, and 1D NMR and 2D NMR data. The sesquiterpenoids were assayed against Escherichia coli, Staphylococcus aureus and Bacillus subtilis. Compounds 4 exhibited weak antibacterial activity against Escherichia coli and Bacillus subtilis.

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KW - Isodaucane

KW - Oppositane

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KW - Sesquiterpenoid

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JO - Chemical and Pharmaceutical Bulletin

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Sesquiterpenoids and other constituents from Senecio argunensis

Abstract

Keywords

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