Predicting protein interactions in human by homologous interactions in yeast

Hyongguen Kim, Jong Park, Kyungsook Han

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

3 Scopus citations

Abstract

As the genes of the human genome become known, one of the challenges is to identify all their interactions. Protein interactions are known for several organisms due to recent improvements in the detection methods for protein interaction, but they are limited to low-order species only. Direct determination of all the interactions occurring between the complete set of human genes remains difficult, even with current large-scale detection methods for protein interaction. This paper presents protein interactions between all human genes using the concept of homologous interaction. We believe this is the first attempt to map a whole human interactome.

Original languageEnglish
Title of host publicationAdvances in Knowledge Discovery and Data Mining
EditorsKyu-Young Wang, Jongwoo Jeon, Kyuseok Shim, Jaideep Srivastava
PublisherSpringer Verlag
Pages159-165
Number of pages7
ISBN (Electronic)3540047603, 9783540047605
DOIs
StatePublished - 2003
Event7th Pacific-Asia Conference on Knowledge Discovery and Data Mining, PAKDD 2003 - Seoul, Korea, Republic of
Duration: 30 Apr 20032 May 2003

Publication series

NameLecture Notes in Artificial Intelligence (Subseries of Lecture Notes in Computer Science)
Volume2637
ISSN (Print)0302-9743

Conference

Conference7th Pacific-Asia Conference on Knowledge Discovery and Data Mining, PAKDD 2003
Country/TerritoryKorea, Republic of
CitySeoul
Period30/04/032/05/03

Bibliographical note

Publisher Copyright:
© Springer-Verlag Berlin Heidelberg 2003.

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