Phytochemicals

Shin Hae Lee, Kyung Jin Min

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

5 Scopus citations

Abstract

Methods for living longer and healthier have attracted the attention of both the public and researchers. One interesting method for inducing a longer and healthier life is dietary supplementation with plant-derived phytochemicals. Phytochemicals are secondary metabolites of plants that function to protect the plant from environmental stresses and provide beneficial effects on the health of animals that consume them. Those effects are the result of the phytochemical’s biological activities including antioxidation, antiinflammation, and cytotoxic activities. Many phytochemicals are reported to have beneficial effects on age-related diseases including cancer, diabetes, immune disease, inflammation, and neurodegenerative diseases. In addition, phytochemicals have been reported to extend the lifespan of experimental animals including yeast, worms, flies, fish, and mice. In this chapter, we summarize and review phytochemicals, such as resveratrol, curcumin, catechin, and quercetin, that have been widely reported to have life-extending effects, and we discuss the putative underlying mechanisms related to the prolongevity effect of phytochemicals.

Original languageEnglish
Title of host publicationEncyclopedia of Biomedical Gerontology
PublisherElsevier
Pages35-47
Number of pages13
ISBN (Electronic)9780128160763
ISBN (Print)9780128160756
DOIs
StatePublished - 1 Jan 2019

Bibliographical note

Publisher Copyright:
© 2019 Elsevier Inc. All rights reserved.

Keywords

  • Calorie restriction
  • Catechin
  • Curcumin
  • Life extension
  • Phytochemicals
  • Quercetin
  • Resveratrol
  • Xenohormesis

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