Photobiomodulation Therapy in Mice with Chronic Cerebral Hypoperfusion Using Application-Specific Near-Infrared Light-Emitting Diode System

Dong Jin Lee; Ha Young Jang; Ki Wook Moon; Eun Joo Lee; A. Ram Yoo; Woo Sung Choi; Chang Kyu Sung; Dae Yu Kim

doi:10.1007/s42341-019-00132-8

Photobiomodulation Therapy in Mice with Chronic Cerebral Hypoperfusion Using Application-Specific Near-Infrared Light-Emitting Diode System

Dong Jin Lee, Ha Young Jang, Ki Wook Moon, Eun Joo Lee, A. Ram Yoo, Woo Sung Choi, Chang Kyu Sung, Dae Yu Kim

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The effective delivery of light energy from the light source to the subject is essential for an increase of therapeutic usefulness in the photobiomodulation therapy. Here, we demonstrate the application-specific near-infrared (NIR) LED therapy system applicable to the mouse for brain repair. The proposed NIR LED therapy system especially employ the curved-shape NIR LED module and the LED dimmer for optimal transfer of the light energy to the mouse brain. The therapeutic effects are evaluated in mice with chronic cerebral hypoperfusion by the positron emission tomographic scans. In the near future, we would like to quantitatively validate the therapeutic effect of our proposed NIR LED therapy system on mice with brain injury and apply it to a human brain.

Original language	English
Pages (from-to)	420-425
Number of pages	6
Journal	Transactions on Electrical and Electronic Materials
Volume	20
Issue number	5
DOIs	https://doi.org/10.1007/s42341-019-00132-8
State	Published - 1 Oct 2019

Bibliographical note

Publisher Copyright:
© 2019, The Korean Institute of Electrical and Electronic Material Engineers.

Keywords

Application-specific NIR LED therapy system
Mouse with vascular dementia
Near-infrared light
Photobiomodulation
Positron emission tomography

Access to Document

10.1007/s42341-019-00132-8

Cite this

@article{639386cafdb74287867d3f1b4e05eb16,

title = "Photobiomodulation Therapy in Mice with Chronic Cerebral Hypoperfusion Using Application-Specific Near-Infrared Light-Emitting Diode System",

abstract = "The effective delivery of light energy from the light source to the subject is essential for an increase of therapeutic usefulness in the photobiomodulation therapy. Here, we demonstrate the application-specific near-infrared (NIR) LED therapy system applicable to the mouse for brain repair. The proposed NIR LED therapy system especially employ the curved-shape NIR LED module and the LED dimmer for optimal transfer of the light energy to the mouse brain. The therapeutic effects are evaluated in mice with chronic cerebral hypoperfusion by the positron emission tomographic scans. In the near future, we would like to quantitatively validate the therapeutic effect of our proposed NIR LED therapy system on mice with brain injury and apply it to a human brain.",

keywords = "Application-specific NIR LED therapy system, Mouse with vascular dementia, Near-infrared light, Photobiomodulation, Positron emission tomography",

author = "Lee, \{Dong Jin\} and Jang, \{Ha Young\} and Moon, \{Ki Wook\} and Lee, \{Eun Joo\} and Yoo, \{A. Ram\} and Choi, \{Woo Sung\} and Sung, \{Chang Kyu\} and Kim, \{Dae Yu\}",

note = "Publisher Copyright: {\textcopyright} 2019, The Korean Institute of Electrical and Electronic Material Engineers.",

year = "2019",

month = oct,

day = "1",

doi = "10.1007/s42341-019-00132-8",

language = "English",

volume = "20",

pages = "420--425",

journal = "Transactions on Electrical and Electronic Materials",

issn = "1229-7607",

publisher = "The Korean Institute of Electrical and Electronic Material Engineers",

number = "5",

}

TY - JOUR

T1 - Photobiomodulation Therapy in Mice with Chronic Cerebral Hypoperfusion Using Application-Specific Near-Infrared Light-Emitting Diode System

AU - Lee, Dong Jin

AU - Jang, Ha Young

AU - Moon, Ki Wook

AU - Lee, Eun Joo

AU - Yoo, A. Ram

AU - Choi, Woo Sung

AU - Sung, Chang Kyu

AU - Kim, Dae Yu

PY - 2019/10/1

Y1 - 2019/10/1

N2 - The effective delivery of light energy from the light source to the subject is essential for an increase of therapeutic usefulness in the photobiomodulation therapy. Here, we demonstrate the application-specific near-infrared (NIR) LED therapy system applicable to the mouse for brain repair. The proposed NIR LED therapy system especially employ the curved-shape NIR LED module and the LED dimmer for optimal transfer of the light energy to the mouse brain. The therapeutic effects are evaluated in mice with chronic cerebral hypoperfusion by the positron emission tomographic scans. In the near future, we would like to quantitatively validate the therapeutic effect of our proposed NIR LED therapy system on mice with brain injury and apply it to a human brain.

AB - The effective delivery of light energy from the light source to the subject is essential for an increase of therapeutic usefulness in the photobiomodulation therapy. Here, we demonstrate the application-specific near-infrared (NIR) LED therapy system applicable to the mouse for brain repair. The proposed NIR LED therapy system especially employ the curved-shape NIR LED module and the LED dimmer for optimal transfer of the light energy to the mouse brain. The therapeutic effects are evaluated in mice with chronic cerebral hypoperfusion by the positron emission tomographic scans. In the near future, we would like to quantitatively validate the therapeutic effect of our proposed NIR LED therapy system on mice with brain injury and apply it to a human brain.

KW - Application-specific NIR LED therapy system

KW - Mouse with vascular dementia

KW - Near-infrared light

KW - Photobiomodulation

KW - Positron emission tomography

UR - http://www.scopus.com/inward/record.url?scp=85073237666&partnerID=8YFLogxK

U2 - 10.1007/s42341-019-00132-8

DO - 10.1007/s42341-019-00132-8

M3 - Article

AN - SCOPUS:85073237666

SN - 1229-7607

VL - 20

SP - 420

EP - 425

JO - Transactions on Electrical and Electronic Materials

JF - Transactions on Electrical and Electronic Materials

IS - 5

ER -

Photobiomodulation Therapy in Mice with Chronic Cerebral Hypoperfusion Using Application-Specific Near-Infrared Light-Emitting Diode System

Abstract

Bibliographical note

Keywords

Access to Document

Other files and links

Fingerprint

Cite this