Phorbaketals A, B, and C, sesterterpenoids with a spiroketal of hydrobenzopyran moiety isolated from the marine sponge phorbas sp

Jung Rae Rho; Buyng Su Hwang; Chung Ja Sim; Seewon Joung; Hee Yoon Lee; Hyeon Jin Kim

doi:10.1021/ol902223m

Phorbaketals A, B, and C, sesterterpenoids with a spiroketal of hydrobenzopyran moiety isolated from the marine sponge phorbas sp

Jung Rae Rho, Buyng Su Hwang, Chung Ja Sim, Seewon Joung, Hee Yoon Lee, Hyeon Jin Kim

Research output: Contribution to journal › Article › peer-review

59 Scopus citations

Abstract

[Chemical Equation Presented] Three new sesterterpenolds, phorbaketals A (1), B (2), and C (3) which have a splroketal of the hydrobenzopyran moiety, were Isolated from the Korean marine sponge Phorbas sp. Their complete structures were elucidated by spectral and chemical methods. They exhibited moderate cytotoxicity against human colorectal, hepatoma, and lung cancer cell lines. Furthermore, the cultivation of the bacterial fraction from the sponge afforded compound 1.

Original language	English
Pages (from-to)	5590-5593
Number of pages	4
Journal	Organic Letters
Volume	11
Issue number	24
DOIs	https://doi.org/10.1021/ol902223m
State	Published - 17 Dec 2009
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1021/ol902223m

Cite this

@article{79e84fb86fd54cb4a094c0e213e395f8,

title = "Phorbaketals A, B, and C, sesterterpenoids with a spiroketal of hydrobenzopyran moiety isolated from the marine sponge phorbas sp",

abstract = "[Chemical Equation Presented] Three new sesterterpenolds, phorbaketals A (1), B (2), and C (3) which have a splroketal of the hydrobenzopyran moiety, were Isolated from the Korean marine sponge Phorbas sp. Their complete structures were elucidated by spectral and chemical methods. They exhibited moderate cytotoxicity against human colorectal, hepatoma, and lung cancer cell lines. Furthermore, the cultivation of the bacterial fraction from the sponge afforded compound 1.",

author = "Rho, {Jung Rae} and Hwang, {Buyng Su} and Sim, {Chung Ja} and Seewon Joung and Lee, {Hee Yoon} and Kim, {Hyeon Jin}",

year = "2009",

month = dec,

day = "17",

doi = "10.1021/ol902223m",

language = "English",

volume = "11",

pages = "5590--5593",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

number = "24",

}

TY - JOUR

T1 - Phorbaketals A, B, and C, sesterterpenoids with a spiroketal of hydrobenzopyran moiety isolated from the marine sponge phorbas sp

AU - Rho, Jung Rae

AU - Hwang, Buyng Su

AU - Sim, Chung Ja

AU - Joung, Seewon

AU - Lee, Hee Yoon

AU - Kim, Hyeon Jin

PY - 2009/12/17

Y1 - 2009/12/17

N2 - [Chemical Equation Presented] Three new sesterterpenolds, phorbaketals A (1), B (2), and C (3) which have a splroketal of the hydrobenzopyran moiety, were Isolated from the Korean marine sponge Phorbas sp. Their complete structures were elucidated by spectral and chemical methods. They exhibited moderate cytotoxicity against human colorectal, hepatoma, and lung cancer cell lines. Furthermore, the cultivation of the bacterial fraction from the sponge afforded compound 1.

AB - [Chemical Equation Presented] Three new sesterterpenolds, phorbaketals A (1), B (2), and C (3) which have a splroketal of the hydrobenzopyran moiety, were Isolated from the Korean marine sponge Phorbas sp. Their complete structures were elucidated by spectral and chemical methods. They exhibited moderate cytotoxicity against human colorectal, hepatoma, and lung cancer cell lines. Furthermore, the cultivation of the bacterial fraction from the sponge afforded compound 1.

UR - http://www.scopus.com/inward/record.url?scp=72849121737&partnerID=8YFLogxK

U2 - 10.1021/ol902223m

DO - 10.1021/ol902223m

M3 - Article

C2 - 19921795

AN - SCOPUS:72849121737

SN - 1523-7060

VL - 11

SP - 5590

EP - 5593

JO - Organic Letters

JF - Organic Letters

IS - 24

ER -

Phorbaketals A, B, and C, sesterterpenoids with a spiroketal of hydrobenzopyran moiety isolated from the marine sponge phorbas sp

Abstract

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this