Abstract
Since the publication of the complete genome sequence of Synechocystis sp. PCC6803, an enormous amount of genomic data for microalgae has been made available on the web. As of November 2013, genome information for 39 cyanobacteria and 24 eukaryotic microalgae is publicly accessible. Additionally, the development of high-throughput omics technologies has driven the accumulation of information on microalgal metabolism. With the evolution of omics technologies, systems biology has become a tool for processing massive amounts of omics data; it has revealed global microalgal metabolic networks and enhanced our understanding of cellular physiology and regulation. Using in silico models of microalgae generated by systems biology, researchers can investigate the photosynthetic pathways that convert inorganic carbon to organic carbon and cellular responses to environmental changes. Such studies will provide opportunities for enhancing microalgal biomass and productivity.
| Original language | English |
|---|---|
| Title of host publication | Handbook of Marine Microalgae |
| Subtitle of host publication | Biotechnology Advances |
| Publisher | Elsevier Inc. |
| Pages | 353-370 |
| Number of pages | 18 |
| ISBN (Electronic) | 9780128011249 |
| ISBN (Print) | 9780128007761 |
| DOIs | |
| State | Published - 1 Jun 2015 |
Bibliographical note
Publisher Copyright:© 2015 Elsevier Inc. All rights reserved.
Keywords
- Cell factories
- In silico model
- Metabolic networks
- Metabolic reconstruction
- Systems biology