Abstract
Norovirus is notorious for foodborne illnesses all over the world. Herein, we introduce a lateral flow assay(LFA) using peptide-functionalized gold nanoparticles(AuNPs) for the detection of norovirus virus-like particles. Anti-norovirus peptides as probes were conjugated to AuNPs and its detection performance was evaluated. As a result, the visual limit of detection with NoroBP-nonfoul-(FlexL)2 in LFA reaches as low as 107 particles/ml. The results indicate that NoroBP-nonfoul-(FlexL)2 has a potential as a novel type of LFA system for easy-to-use, cost-effective, and point-of-care diagnostic platform.
| Original language | English |
|---|---|
| Title of host publication | MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 1218-1219 |
| Number of pages | 2 |
| ISBN (Electronic) | 9781733419017 |
| State | Published - 2020 |
| Event | 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020 - Virtual, Online Duration: 4 Oct 2020 → 9 Oct 2020 |
Publication series
| Name | MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
|---|
Conference
| Conference | 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020 |
|---|---|
| City | Virtual, Online |
| Period | 4/10/20 → 9/10/20 |
Bibliographical note
Publisher Copyright:© 2020 CBMS-0001
Keywords
- Affinity peptide
- Colorimetric
- Lateral flow assay
- Norovirus detection