Hydroxyapatite mineralization on the calcium chloride blended polyurethane nanofiber via biomimetic method

R. Nirmala, Ki Taek Nam, R. Navamathavan, Soo Jin Park, Hak Yong Kim

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Polyurethane nanofibers containing calcium chloride (CaCl 2) were prepared via an electrospinning technique for the biomedical applications. Polyurethane nanofibers with different concentration of CaCl 2 were electrospun, and their bioactivity evaluation was conducted by incubating in biomimetic simulated body fluid (SBF) solution. The morphology, structure and thermal properties of the polyurethane/CaCl 2 composite nanofibers were characterized by means of scanning electron microscopy (SEM), field-emission scanning electron microscopy, energy dispersive X-ray spectroscopy, X-ray diffraction, Fourier transform infrared spectroscopy and thermogravimetry. SEM images revealed that the CaCl 2 salt incorporated homogeneously to form well-oriented nanofibers with smooth surface and uniform diameters along their lengths. The SBF incubation test confirmed the formation of apatite-like materials, exhibiting enhanced bioactive behavior of the polyurethane/CaCl 2 composite nanofibers. This study demonstrated that the electrospun polyurethane containing CaCl 2 composite nanofibers enhanced the in vitro bioactivity and supports the growth of apatite-like materials.

Original languageEnglish
Article number2
Pages (from-to)1-8
Number of pages8
JournalNanoscale Research Letters
Volume7
DOIs
StatePublished - 2012
Externally publishedYes

Bibliographical note

Funding Information:
This study was supported by the Agency for Defense Development (UE105118GD), Republic of Korea.

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