TY - JOUR
T1 - Extraction and purification of depigmenting agents from Chinese plants
AU - Jin, Yin Zhe
AU - Li, Guang Hua
AU - Ahn, So Young
AU - Row, Kyung Ho
AU - Kim, Eun Ki
PY - 2006/3
Y1 - 2006/3
N2 - Depigmenting agents were solvent-extracted and purified by preparative and analytical HPLC from three Chinese plants; Chrysanthemum morifolium Ramat(Xizang Caijuhua), Rhodiola sachalinensis, and Terminalia chebula Retzius. Four fractions obtained from the ethyl ether layer of C. m. Rama and two fractions from the ethyl acetate layer of Rhodiola salientness show depigmenting effects. At δ 200, the ethyl acetate layers of Chrysanthemum morifolium Ramat, Rhodiola sachalinensis and the methanol extract of Terminalia chebula Retzius, can inhibit the melanin production of mouse B16 melanoma cells by 92%, 60% and 90%, respectively, whereas 46% inhibition was observed by commercially available depigmenting agents(arbutin). These results show the potential of these three Chinese plants as a novel resource for depigmenting agents in the cosmetic industry.
AB - Depigmenting agents were solvent-extracted and purified by preparative and analytical HPLC from three Chinese plants; Chrysanthemum morifolium Ramat(Xizang Caijuhua), Rhodiola sachalinensis, and Terminalia chebula Retzius. Four fractions obtained from the ethyl ether layer of C. m. Rama and two fractions from the ethyl acetate layer of Rhodiola salientness show depigmenting effects. At δ 200, the ethyl acetate layers of Chrysanthemum morifolium Ramat, Rhodiola sachalinensis and the methanol extract of Terminalia chebula Retzius, can inhibit the melanin production of mouse B16 melanoma cells by 92%, 60% and 90%, respectively, whereas 46% inhibition was observed by commercially available depigmenting agents(arbutin). These results show the potential of these three Chinese plants as a novel resource for depigmenting agents in the cosmetic industry.
KW - Chrysanthemum Morifolium Ramat
KW - HPLC
KW - Melanin Inhibitory Effect
KW - Rhodiola Sachalinensis
KW - Terminalia Chebula Retzius
UR - http://www.scopus.com/inward/record.url?scp=33646370215&partnerID=8YFLogxK
U2 - 10.1016/S1005-9040(06)60067-6
DO - 10.1016/S1005-9040(06)60067-6
M3 - Article
AN - SCOPUS:33646370215
SN - 1005-9040
VL - 22
SP - 162
EP - 167
JO - Chemical Research in Chinese Universities
JF - Chemical Research in Chinese Universities
IS - 2
ER -