Abstract
A new bakkenolide and a known one were isolated from Petasites tatewakianus. The structure of the new compound was elucidated on the basis of spectroscopic methods including IR, EIMS, HRESIMS, 1D and 2D NMR, and the known compound was established by single crystal X-ray structural analysis. The in vitro cytotoxic activity of these two compounds against cultured human cervical carcinoma (HeLa), human breast cancer (MCF-7) and murine Lewis lung carcinoma (LLC) cell lines was also evaluated.
Original language | English |
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Pages (from-to) | 153-156 |
Number of pages | 4 |
Journal | Fitoterapia |
Volume | 81 |
Issue number | 3 |
DOIs | |
State | Published - Apr 2010 |
Bibliographical note
Funding Information:This work was financial supported by State Key Laboratory of Applied Organic Chemistry, Lanzhou University, P. R. China .
Keywords
- Bakkenolide
- Compositae
- Petasites tatewakianus
- Sesquiterpene