Bakkenolides from Petasites tatewakianus

Xie Wei Dong, Rui Juan Li, Xue Gao, Kyung Ho Row

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

A new bakkenolide and a known one were isolated from Petasites tatewakianus. The structure of the new compound was elucidated on the basis of spectroscopic methods including IR, EIMS, HRESIMS, 1D and 2D NMR, and the known compound was established by single crystal X-ray structural analysis. The in vitro cytotoxic activity of these two compounds against cultured human cervical carcinoma (HeLa), human breast cancer (MCF-7) and murine Lewis lung carcinoma (LLC) cell lines was also evaluated.

Original languageEnglish
Pages (from-to)153-156
Number of pages4
JournalFitoterapia
Volume81
Issue number3
DOIs
StatePublished - Apr 2010

Bibliographical note

Funding Information:
This work was financial supported by State Key Laboratory of Applied Organic Chemistry, Lanzhou University, P. R. China .

Keywords

  • Bakkenolide
  • Compositae
  • Petasites tatewakianus
  • Sesquiterpene

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