Application of ionic liquids in high performance reversed-phase chromatography

Ye Wang, Minglei Tian, Wentao Bi, Ho Row Kyung

Research output: Contribution to journalReview articlepeer-review

94 Scopus citations

Abstract

Ionic liquids, considered "green" chemicals, are widely used in many areas of analytical chemistry due to their unique properties. Recently, ionic liquids have been used as a kind of novel additive in separation and combined with silica to synthesize new stationary phase as separation media. This review will focus on the properties and mechanisms of ionic liquids and their potential applications as mobile phase modifier and surface-bonded stationary phase in reversed-phase high performance liquid chromatography (RP-HPLC). Ionic liquids demonstrate advantages and potential in chromatographic field.

Original languageEnglish
Pages (from-to)2591-2610
Number of pages20
JournalInternational Journal of Molecular Sciences
Volume10
Issue number6
DOIs
StatePublished - Jun 2009

Keywords

  • Additives
  • Ionic liquids
  • Reversed-phase high performance liquid chromatography
  • Stationary phase

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