Application of ionic liquid for extraction and separation of bioactive compounds from plants

Baokun Tang, Wentao Bi, Minglei Tian, Kyung Ho Row

Research output: Contribution to journalReview articlepeer-review

222 Scopus citations

Abstract

In recent years, ionic liquids (ILs), as green and designer solvents, have accelerated research in analytical chemistry. This review highlights some of the unique properties of ILs and provides an overview of the preparation and application of IL or IL-based materials to extract bioactive compounds in plants. IL or IL-based materials in conjunction with liquid-liquid extraction (LLE), ultrasonic-assisted extraction (UAE), microwave-assisted extraction (MAE), high performance liquid chromatography (HPLC) and solid-phase extraction (SPE) analytical technologies etc., have been applied successfully to the extraction or separation of bioactive compounds from plants. This paper reviews the available data and references to examine the advantages of IL and IL-based materials in these applications. In addition, the main target compounds reviewed in this paper are bioactive compounds with multiple therapeutic effects and pharmacological activities. Based on the importance of the targets, this paper reviews the applications of ILs, IL-based materials or co-working with analytical technologies. The exploitation of new applications of ILs on the extraction of bioactive compounds from plant samples is expected to increase.

Original languageEnglish
Pages (from-to)1-21
Number of pages21
JournalJournal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
Volume904
DOIs
StatePublished - 1 Sep 2012

Bibliographical note

Funding Information:
This study was supported by Basic Science Research Program through the National Research Foundation (NRF) of Korea funded by the Ministry of Education, Science and Technology ( 2012-0005250 ).

Keywords

  • Bioactive compound
  • Extraction
  • Ionic liquid
  • Plant
  • Separation

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